The Handshake Initiative is a global organization that bridges divides by connecting diverse stakeholders - governments, businesses, NGOs, and individuals - to work together on critical challenges related to the UN's Sustainable Development Goals for good health, education, gender equality, reduced inequalities, climate action, and peace and justice. We empower these cross-sector partnerships through collaborative training, resources, and knowledge sharing to drive effective joint action. Our work amplifies high-impact, partnership-driven solutions by advocating for supporting policies and scaling proven approaches, ultimately fostering a healthier, more equitable, and sustainable future through the power of collaborative action.